Genetic testing can make a major contribution to the fight against Coronavirus / COVID-19. Find out how a simple saliva test can help hospitals manage during the coronavirus outbreak.
Pharmacogenomics Testing
What is Personalised Medicine?
Personalised medicine is the tailoring of medical treatment to the individual needs and preferences of a patient during all stages of care including prevention, diagnosis, treatment and follow-up.
Many patients do not benefit from the first drug they are offered in treatment. For Example 38% of depression patients, 50% of arthritis patients, 40% of asthma patients and 43% of diabetic patients will not respond to initial treatment. *
Personalised medicine has the phenomenal ability, over time, to reduce these figures dramatically.
What is Pharmacogenomics?
Pharmacogenomics is one of the branches of personalised medicine. Pharmacogenomics is the study of how your genetic makeup can affect your response to medication. It uses information about your genes to determine the medication – and the dosage – that is most likely to work for you.
* Spear BB, Heath-Chiozzi M, Huff J. Clinical application of pharmacogenetics. Trends Mol Med. 2001; 7(5):201-4.
What are the Benefits
of Pharmacogenomics?
By having access to your genetic data, your doctor eliminates a ‘one size fits all’ mentality and will develop a personal treatment plan that’s relevant for you and you only.
Pharmacogenomics covers 3 topics:
- Whether a medication may be an effective treatment for you
- What is the best dose of a medication for you
- Whether you could have serious side effects from a medication
What is a Pharmacogenomics test?
How do i do the Test?
The test is nothing more than a simple saliva test and you can do it yourself at home or in the doctor’s office. The sample is sent to our laboratory and the results are ready in around 2-3 weeks. Read more about taking the test HERE .
Who Sees the Results?Are They Confidential?
Only you and your doctor will see the results as they are confidential.
What are the Benefits of the Test Results?
Once your doctor has seen and analysed your test results, he or she will know precisely what to prescribe and at what dose. The beauty of having this test done is that since your genetic makeup doesn’t change with age, the results remain relevant and they can be used whenever you require prescription medicine.
When is Pharmacogenomics Testing Recommended?
Testing is recommended for anyone, regardless of age, who is or who may be about to receive prescribed medications with indicated pharmacogenomic biomarkers. In particular:
- when there is more than one drug to choose from
- patients taking drugs with high incidence or serious side effects
- when the starting dosage is not clear
- patients who are taking more than one drug
What Does the
PG x ONE™ Plus Test Cover?
PGxOne™ Plus is a pharmacogenetic test that comprehensively assays 50 well-established pharmacogenomic genes and detects ~200 variants and CNVs (Copy Number Variants) in a single, cost-effective test.
Clinical specialities include:
Cardiology • Psychiatry • Pain Management • Oncology • Infectious Disease • AIM • Endocrinology • Neurology • Rheumatology • Gastroenterology • Immunology • Urology
Advanced next-generation sequencing technology allows us, for the first time, to give blanket coverage to variants in 50 genes and the results are delivered quickly.
You will be provided with an easy-to-read, clinically relevant and medically actionable report which you can go through with your patient.
What Genes Are Screened?
Acknowledged by multiple regulatory bodies, the 50 genes PGxOne™ Plus is validated to screen are listed below. The test screens clinically-relevant and medically actionable variations within these genes, taking in the activity of over 220 commercial drugs.
ABCB1
ATM
CYP2B6
CYP3A5
F2
HLA-B
KIF6
SCN2A
VKORC1
ACE
CDA
CYP2C19
CYP4F2
F5
HTR1A
MTHFR
SLC6A4
XRCC1
ADRA2A
CES1
CYP2C8
DPYD
FAAH
HTR2A
NAT2
SLCO1B1
AGTR1
CNR1
CYP2C9
DRD1
G6PD
HTR2C
NOS1AP
TPMT
ANKK1
COMT
CYP2D6
DRD2
GRIK4
IFNL3
NQO1
UGT1A1
APOE
CYP1A2
CYP3A4
ERCC1
GSTP1
ITPA
OPRM1
UGT2B15
Who is Responsible for Interpreting the Test Results?
The laboratory we use interprets the results and will send your doctor a clear, easy to understand report.
How Accurate are the Results?
PGxOne™ Plus sequencing data (variant detection) has been validated by direct comparison to data generated by Sanger sequencing, considered the gold-standard DNA sequencing technique by the world’s largest life sciences laboratories. The PGxOne™ Plus test displayed 100% sensitivity (true positive detection rate) and 100% specificity (true negative detection rate).
Arrange your Pharmacogenomics test NOW
Email us now to arrange your PGxOne™ test
Email us now at [email protected] to find out how we can answer all your questions and help put your mind at rest. Our PGxOne test process is simple, fast and effective.
Call us now to arrange your PGxOne™ test
Call us now on 0208-387-1266 to arrange a Phacrmacogenomics test and find out how personalised medicine (Myogenes Genetic Testing UK) can help you find your fastest route to health. The PGxOne™test process is simple and fast.