DRAFT – The Hereditary Cancer Screening Test
Information is power. Early cancer detection dramatically improves your chances of beating it. Our Hereditary Cancer Screening Test, designed for anyone over 18 years old, allows you to find out your risk levels and manage your health proactively.
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What the test is and how it works
We all know that early cancer detection can dramatically improve your chances of survival. It has been discovered that inherited genetic mutations can increase the chance of developing cancer in the future. So, with all that in mind, our test specifically looks for mutations in genes associated with a number of Hereditary Cancers, including Breast, Ovarian, Prostate, Colon, Stomach, Head and Neck cancers.
Once your saliva sample has been analysed by our experts, a detailed report that includes information on the presence, or absence of mutations associated with increased cancer risk will be sent to your doctor within 3 weeks. You’ll then have the chance to go through the results together, and your doctor can explain any findings or next steps if they’re required.
To see the full list of genes we test, please click here.
Who this test is for
This test can be taken by anyone over the age of 18, including healthy individuals who just want to know if they’re at an increased risk of cancer later in life. However, we specifically recommend it for the following:
- Individuals in certain ethnic groups, such as Ashkenazi Jewish that have an increased risk (1 in 40) for certain cancers.
- Individuals with a family history of cancer. This means a combination (usually 2 or more) of cancers on the same side of the family.
- Individuals who have a family member with breast, colorectal, endometrial, and possibly other cancers before the age of 50.
- Individuals with a family member with a rare form of cancer at any age (i.e. triple-negative breast cancer, ovarian cancer)
- Individuals with cancer who want to understand if their cancer was hereditary, and if they are at an increased risk for other cancers.
Knowledge is power, and early cancer detection dramatically improves your chances of a cure. Knowing your risk levels can enable you to manage your health proactively. For example, you can work with your doctor on a screening programme that may start at a younger age to help detect cancer at the earliest possible stage. If your test highlights mutations, then your doctor may prescribe preventative medication to reduce cancer risks, and individuals who are deemed at higher risk for cancer may also benefit from risk-reducing surgery.
Your family members can also determine their risk status and take charge of their own personal health. Parents, siblings, and children have up to a 50% chance of carrying the same mutation. If your test highlights mutations, your immediate family can be tested for that the particular gene mutation for only £99.00 including VAT.
On the other hand, learning that you do not carry a gene variant that predisposes to hereditary cancer risk is also valuable and reassuring information.
What does a positive test mean?
If your predictive genetic test result is positive, it means you have a faulty gene that raises your risk of developing cancer. However, it’s important to understand that it doesn’t mean you are guaranteed to get cancer in the future. Your genes only partly influence your future health risks. Other factors, such as your medical history, lifestyle and your environment, also play a key role.
Your test and results
At Myogenes we use a state-of-the-art genetic test developed by Invitae for identifying hereditary cancer susceptibility mutations. The test uses advanced next-generation sequencing (SMSEQTM) targeting 61 genes with a high degree of analytical sensitivity and specificity. Validation using industry-standard methods yielded an accuracy of 99.99%. The genetic panel includes 61 genes reported in the literature as being associated with increased risk for a number of hereditary cancers, including breast, ovarian, prostate cancer.