genes

Myogenes FAQ

Answers to the most common questions we get asked

All Myogenes Genetic Testing UK genetic tests are all done using DNA extracted from saliva. We are not using blood tests. This saliva testing can be done in your home, your office or at one of our registered doctors. Please call us to discuss the genetic tests that we offer at Myogenes, or Fill out the contact form and one of our team will contact you. This FAQ covers the most common questions that we recieve.

The Science Behind Myogenes Genetic Testing FAQ

What is a gene and what are mutations?

A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people.Mutations range in size; they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes.

What are genetic diseases?

A genetic disorder is a condition that is caused by an abnormality in an individual’s DNA. Abnormalities can be as small as a single-base mutation in just one gene, or they can involve the addition or subtraction of entire chromosomes.

What can be diagnosed with genetic tests?

Diagnostic testing is used to identify or rule out a specific genetic or chromosomal condition. In many cases, genetic testing is used to confirm a diagnosis when a particular condition is suspected based on physical signs and symptoms.

Why are mutations dangerous?

Because these mutations have very serious effects, they are incompatible with life. It is important to note that genes themselves do not cause disease—genetic disorders are caused by mutations that make a gene function improperly.

If a mutation is passed down, will it always cause a disease?

No it doesn’t. However, our cancer test (see Cancer FAQ below) will tell you if you have inherited an abnormal version of the BRCA gene

Does the analysis reveal anything about my risk of serious disease?

No it doesn’t. However, our cancer test (see Cancer FAQ below) will tell you if you have inherited an abnormal version of the BRCA gene

How is a DNA Genetic test different from an ancestral genetic test?

We do not offer Genetic ancestry testing, or genetic genealogy. That is a way for people interested in family history to go beyond what they can learn from relatives or from historical documentation. At Myogenes, we are using your genetics to analyse your health.

What are the advantages of genetic testing & how is it useful?

Test results can provide a sense of relief from uncertainty and help people make informed decisions about managing their health care. For example, a negative result can eliminate the need for unnecessary checkups and screening tests in some cases. A positive result can direct a person toward available prevention, monitoring, and treatment options.

Pharmacogenomics Testing FAQ

What is 'Pharmacogenomics?'

Pharmacogenomics is one of the branches of personalised medicine. Pharmacogenomics is the study of how your genetic makeup can affect your response to medication. It uses information about your genes to determine the medication – and the dosage – that is most likely to work for you.

What topics does the Pharmacogenomics test offer?

  • Whether a medication may be an effective treatment for you
  • What is the best dose of a medication for you
  • Whether you could have serious side effects from a medication

How long will my results take?

3 weeks 

Will there be a professional to go through results with me?

Yes, for an extra cost, you will be able to have a consultation with a medical professional who will go through your results.

What will be the format of my results?

A comprehensive report (20-30 pages) 

How much is the test?

£600 including VAT 

What are the benefits of having the test?

Once your doctor has seen and analysed your test results, he or she will know precisely what to prescribe and at what dose. The beauty of having this test done is that since your genetic makeup doesn’t change with age, the results remain relevant and they can be used whenever you require prescription medicine.

When is Pharmacogenomics Testing Recommended?

  • when there is more than one drug to choose from
  • patients taking drugs with high incidence or serious side effects
  • when the starting dosage is not clear
  • patients who are taking more than one drug

How accurate are the results?

PGxOne™ Plus sequencing data (variant detection) has been validated by direct comparison to data generated by Sanger sequencing, considered the gold-standard DNA sequencing technique by the world’s largest life sciences laboratories. The PGxOne™ Plus test displayed 100% sensitivity (true positive detection rate) and 100% specificity (true negative detection rate).

What does the test cover?

Cardiology • Psychiatry • Pain Management • Oncology • Infectious Disease • AIM • Endocrinology • Neurology • Rheumatology • Gastroenterology • Immunology • Urology

The Genetic Testing Procedure FAQ

Is the test available for those living outside the UK?

Yes. Although Myogenes is a UK based diagnostic company,  our tests are available anywhere in the world. 

From what age can a child be tested?

According to clinical testing, there is no age limitation for genetic testing.

Can you take the test if you are pregnant?

According to clinical testing, pregnancy does not affect genetic testing.

If you are on medication, can you take a genetic test?

According to clinical testing, medication does not affect genetic testing.

Prior to taking the test, do you need access to my medical records?

No, we do not need access to medical records.

Does it hurt to take a sample and are there instructions?

It is a simple swab test causing no pain (instructions will be sent to you & tutorial video is available upon request)

Who has access to a person’s genetic test results? Are they confidential?

Your results are data protected and requires a password – our staff cannot access an individual’s results.

Do I need a referral for genetic testing?

No, our test is open for anybody.

How sure are you that the samples won't be mixed up?

Steps are taken to make sure that will never happen and every test is handled with care and professionalism.  

What are the names of the genetic tests that Myogenes offer?

Pharmacogenomics  
Breast cancer 
Hereditary cancer 
Psychiatric
Health and fitness

I have private health insurance will this cover genetic cancer testing?

No. However, each individual case can be discussed with our team.

Do you offer a refund policy?

No.

Psychiatric Testing FAQ

What psychiatric conditions does the test cover?

  • Depression
  • Anxiety
  • Obsessive-Compulsive Disorder (OCD)
  • Attention Deficit hyperactivity Disorder (ADHD)
  • Bipolar Disorder
  • Post Traumatic Stress Disorder (PTSD)
  • autism
  • schizophrenia
  • chronic pain
  • substance abuse

How long will my results take?

7-10 days 

Will there be a professional to go through results with me?

Yes, for an extra cost, you will be able to have a consultation with a medical professional who will go through your results.

What will be the format of my results?

A comprehensive report (10-20 pages) 

How much is the test?

£715 including VAT

Has the test been proven with clinical evidence?

The Assay has been shown in peer reviewed published studies to improve patient outcomes and reduce overall medical costs. Each Assay provides clinicians with an easy to read patient report and a complimentary psychopharmacogenomic consultation. Genomind is always searching for ways to improve upon the traditional trial and error process of drug prescribing in psychiatry. As such, we have conducted and continue to conduct a number of studies in order to present objective data on how the Genecept Assay® can help patients feel better, faster. Clinical evidence has shown the Genecept Assay has resulted in better treatment response and patient compliance, as well as decreased healthcare costs.

Health & Fitness Testing FAQ

How long will my results take?

4-5 weeks

Will there be a professional to go through results with me?

Yes, for an extra cost,  once you receive your results, you then have the option to have a consultation with one of Myogenes’ professional health specialists/nutritionists.The consultation can be a face to face meeting or by telephone.

How much is the test?

£358 including VAT (can order directly on www.myogenes.com

What exactly is the NutriFit Test?

The NutriFit is a simple saliva DNA test which examines specific genes. Thanks to rapid advances in science, it is now possible to create a personalised diet and lifestyle plan based on your own individual genetic makeup. Every one of us possesses a specific genetic makeup; each one of us, therefore, has specific nutritional needs. NutriFit eliminates the guesswork out of dieting.

What does the health and fitness test help you discover?

The most important micro- and macro-nutrients you need. You will learn about your metabolism of alcohol, coffee and lactose, and your response to various forms of physical activity, including a greater understanding of your muscles and which sports will benefit you. You will find out whether you have a propensity for high cholesterol, high blood sugar, weak bones and/ or obesity.

After taking the health and fitness test, how do you get to your ideal body weight?

You will learn how your genetic makeup influences the development of weight gain and obesity, as well as how your body responds to different types of carbohydrates and fats. The balance between the intake and use of calories, physical activity and your genetic makeup are key to optimal body weight and well-being, and this chapter reveals a ‘diet type’ that, according to your genetic makeup, is ideal for you.

You will discover what type of exercise is most suitable for you based on your muscle structure, as well as finding out if there are certain sporting injuries you may be more prone to. Certain type of sports, recreation and exercise are more beneficial for some than for others, and some can even be detrimental to your health and well-being. With the help of DNA analysis, NutriFit will recommend the type of recreation that suits you best and advise you on the ones that aren’t ideal for you.

How Much do Genes Influence Your Metabolism & Health?

You will discover to what extent levels of ‘bad’ LDL and ‘good’ HDL cholesterol, triglycerides and blood sugar are determined by your genes. Inappropriate levels of any of these components can quickly cause cardiovascular complications, high blood pressure, obesity and diabetes. Your genes determine the fight against external influences such as bad diet, alcohol consumption and smoking, and this will show you what you can do to put yourself on the path to optimal health. You will find out about your response to alcohol, caffeine and lactose according to your genetic makeup, and how effective your body is at processing these common substances.

What are the 8 chapters in the report?

  1. The way to Your Ideal Body Weight
  2. How Much do Genes Influence Your Metabolism & Health?
  3. Which Vitamins & Minerals Does Your Body 
  1. Important Influences on Your Eating Habits
  1. The Effectiveness of Your Metabolism
  1. Your Genes, Detoxification & Antioxidants
  1. Sports & Recreation in Tune With Your Genes
  1. Genetically-Determined Addictions & Ageing 

Breast Cancer & Hereditary Cancer Testing FAQ

What genetic tests are available at Myogenes for cancer risk?

We offer breast and hereditary cancer genetic tests

How long will my results take?

3 weeks 

Will there be a professional to go through results with me?

Yes, for an extra cost, you will be able to have a consultation with a medical professional who will go through your results.

What will be the format of my results?

A comprehensive report (10-20 pages) 

If you have cancer, could the test be covered?

If you have been previously diagnosed with cancer, vitality will cover this.

How much is the test?

BRCA: £650 including VAT 

Hereditary: £750 including VAT 

What kind of mutations can cause cancer?

Acquired mutations are the most common cause of cancer. They occur from damage to genes in a particular cell during a person’s life. Cancer that occurs because of acquired mutations is called sporadic cancer. Acquired mutations are not found in every cell in the body and they are not passed from parent to child.Mutations happen often. A mutation may be beneficial, harmful, or neutral. This depends where in the gene the change occurs. Typically, the body corrects most mutations.  A single mutation will likely not cause cancer. Usually, cancer occurs from multiple mutations over a lifetime. That is why cancer occurs more often in older people. They have had more opportunities for mutations to build up

How can genetic testing help for cancer?

Genetic testing helps estimate your chance of developing cancer in your lifetime. It does this by searching for specific changes in your genes, chromosomes, or proteins. These changes are called mutations.

Does someone who inherits a cancer-predisposing mutation always get cancer?

No.

Are your Myogenes genetic cancer tests the same as the ones offered by the NHS and other companies?

The myogenes test is the most comprehensive on the market with 100% success rate and cannot be matched.

What does the hereditary cancer test identify?

25 hereditary cancers by analyzing 98 genes from your DNA.The test looks for mutations in 98 genes associated with 25 Hereditary Cancers including Breast, Ovarian, Prostate, Colon, Stomach, Head and Neck cancers.The report includes a personalized health risk management plan, enabling you to review with your doctor and take control of your health.You receive a report that includes information on the presence or absence of mutations associated with increased cancer risk.

Who would get the hereditary cancer test done?

Knowing your risk can enable you to manage your health proactively. 

  • Healthy individuals who want to know if they are at an increased risk for cancer.
  • Individuals in certain ethnic groups (eg., Ashkenazi Jewish) that have an increased risk for certain cancers.
  • Individuals with cancer who want to understand if their cancer was hereditary, and if they are at an increased risk for other cancers.
  • Individuals with a family history of cancer

What does a positive breast cancer test mean?

If your predictive genetic test result is positive, it means you have a faulty gene that raises your risk of developing cancer. It doesn’t mean you are guaranteed to get cancer – your genes only partly influence your future health risks. The average lifetime risk of breast cancer for women is about 12%. That’s 1 out of 9 women. For women who have a BRCA1 or BRCA2 mutation, the risk of developing breast cancer in a lifetime is between 40% and 85% – about three to seven times greater than that of a woman who does not have the mutation.

What are the other genes associated with Breast Cancer that the BRCA Test includes?

ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, NBN, NF1, PALB2, PPM1D, PTEN, RAD51C, STK11, TP53

Why Myogenes FAQ

Why should I choose Myogenes for genetic testing?

Myogenes are the most comprehensive brand in this market, offering personalised medicine to a whole new level.  

Can Myogenes experts discuss my results with my current GP?

Yes, this can be arranged.